ea0037oc4.1 | Diabetes | ECE2015
O'Harte Finbarr
, McShane Laura
, Irwin Nigel
Glucagon receptor KO mice are resistant to the clinical manifestations of diabetes induced by streptozotocin (STZ) and retain normal glycaemic control and glucose tolerance. In the present study the effects of chronic (18 days) once daily i.p. administration of two different glucagon receptor antagonists (GRA); desHis1Pro4Glu9-glucagon (GRA-1) and its related acylated peptide desHis1Pro4Glu9(Lys12PAL)...